Docking@Home is a collaborative project that aims to accomplish both bioscience and computer science goals. From the bioscience point of view, the project aims to further knowledge of the atomic details of protein-ligand interactions and, by doing so, will search for insights into the discovery of novel pharmaceuticals. From the computer science point of view, this project aims to extend volunteer computing to enable adaptive multi-scale modeling of the docking applications: different models that represent the same phenomena in nature with different level of accuracy and resource requirements will be chosen at run-time based on results collected so far and characteristics of the protein-ligand complex. Docking@Home involves collaboration among the University of Delaware, The Scripps Research Institute (TSRI), and the University of California - Berkeley and is powered by BOINC. Docking@Home is part of the DAPLDS project (or Dynamically Adaptive Protein-Ligand Docking System project) and is supported by the National Science Foundation (NSF).